Brain Energy has been formulated to help:
- Increase cellular energy levels
- Promote healthy mitochondrial function
- Reduce cognitive fatigue
- Support a healthy stress response
- Promote healthy neurotransmitter synthesis
- Promote healthy neurotransmission
- Reduce homocysteine levels
- Support cardiovascular function
- Maintain healthy cholesterol levels
- Maintain healthy blood sugar levels
AquaCelle Q10® – Coenzyme Q10 (CoQ10)
Coenzyme Q10 (CoQ10) is an essential cofactor in the production of adenosine triphosphate (ATP), the energy currency of all cells and responsible for fueling all the chemical processes that allow the body to live and function properly. A vitamin-like compound, CoQ10 is present in all cells, residing predominantly within the inner membrane of the cells’ mitochondria. Mitochondria are the ‘powerhouse’ of a human cell and where ATP energy is produced. CoQ10 is most concentrated in organs with high energy demands such as the brain and heart.
In addition to helping produce ATP, CoQ10 also acts as a potent antioxidant, helping to protect mitochondria from the damaging free radicals generated during the ATP production process. This antioxidant protection is especially important to brain health, given its high concentration of mitochondria, significant energy demands, and susceptible high-fat content. In addition to its own antioxidant properties, CoQ10 also possesses the ability to regenerate used vitamin E to its original antioxidant form, further extending its antioxidant benefits in the body.
CoQ10 is naturally produced in the body but levels are known to decrease as we age. While some CoQ10 is available through diet, research would suggest those quantities are not enough to support optimal energy production and antioxidant support as we age. Supplementing with CoQ10 can help optimize CoQ10 levels, but standard CoQ10 formulations are poorly absorbed.
AquaCelle Q10® uses an innovative and patented delivery technology to significantly increase the bioavailability of CoQ10 through a clinically-validated self-micro-emulsifying drug delivery system (SMEDDS). The SMEDDS technology aids the absorption of CoQ10, a fat-soluble molecule, in your aqueous (water-based) gastrointestinal environment.
Clinical studies have demonstrated the superior bioavailability of AquaCelle Q10® over standard CoQ10 formulations, achieving 300% better absorption. AquaCelle Q10® also showed bio-equivalence to commercial formulations of CoQ10’s reduced form, known as Ubiquinol.
The AquaCelle Q10® in Brain Energy helps maintain optimal CoQ10 levels, supporting mitochondria function, and enhancing ATP cellular energy production.
Quatrefolic® – Folate
Folate is involved in the production of key neurotransmitters in the brain. Deficiency of Folate is associated with mood disorders and cognitive decline. Research shows a prevalence of deficiency in older populations.
Folate is vital to DNA synthesis, red-blood-cell production, cell division, and the remethylation of homocysteine. High levels of homocysteine is a recognized biomarker associated with cardiovascular health and an increased risk of certain neurodegenerative disorders.
Quatrefolic® is the most advanced form of folate supplementation available on the market. It contains levomefolate glucosamine, a biologically active form of folate known as 5-methyltetrahydrofolate (5-MTFH). Quatrefolic® offers increased stability and bioavailability over dietary folate, folic acid, and other calcium salt-based active forms such as Metafolin.
Quatrefolic® achieves superior bio-availability due to folic acid, and dietary folate’s need to first be converted by the body into the metabolically active 5-MTFH form, before it may enter the body’s all-important folate cycle. Critical to this conversion process is an enzyme called methylenetetrahydrofolate reductase (MTHFR), which many individuals are inadequately able to produce due to their genetics. Deficiencies in the production and function of this enzyme lead to an increase in homocysteine levels. As Quatrefolic® is already in the reduced active 5-MTFH form, it can bypass the MTHFR enzyme process and directly support the nutritional demands irrespective of genetic polymorphisms.
Supplementing with Quatrefolic® will also negate the potential health risks associated with the inferior and more common folic acid supplement form. Folic acid supplements can lead to an accumulation of ‘unmetabolized folic acid (UMFA)’ in the blood, with potentially toxic effects.
Magnesium supports energy metabolism, nerve, and muscle function. High concentrations are found near the mitochondria. Brain Energy has been specially formulated with the highly bioavailable citrate form of Magnesium, due to the citric acid element being an essential component of the citric acid (Kreb’s) cycle. This cycle is the process in which mitochondria produce ATP cellular energy.
Alpha-lipoic acid (ALA) is often referred to as a mitochondrial nutrient due to its influence on mitochondria health and function. ALA’s potent antioxidant properties help protect mitochondria DNA from free radical damage. It also promotes mitochondria ‘biogenesis,’ the process by which cells increase their mitochondria mass. Biogenesis is known to decrease with age and is associated with adverse health effects.
ALA is also a cofactor for two key mitochondria enzymes called pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase. These enzymes support glucose metabolism and ATP cellular energy production.
Vitamin B1, also known as Thiamine, is an essential co-factor in many metabolic processes and is involved in metabolizing food into ATP cellular energy. It is a component of the enzyme Thiamine pyrophosphate (TPP). TPP is crucial for nerve cell function, neurotransmission, and nerve conduction.
Vitamin B1 also plays a vital role in maintaining a healthy brain, muscle, and heart function. It is necessary for normal neurological, psychological, and cardiac function.
Active Form Vitamin B2 (Riboflavin sodium phosphate)
Brain Energy contains the the bio-activated form of vitamin B2 known as Riboflavin sodium phosphate (R5P). This activated form allows for immediate utilization in the body.
Vitamin B2 plays a crucial role in many metabolic processes throughout the body, supporting methylation and also acting as an antioxidant. It plays a vital role in the metabolism of food into ATP cellular energy and assists in the activation and conversion of other B vitamins.
Vitamin B2 contributes to the production of your red blood cells and the maintenance of healthy thyroid and adrenal function. It is also involved in the metabolism of homocysteine.
Vitamin B3, also known as nicotinamide, like the other B vitamins, helps with the metabolism of food and its conversion into ATP cellular energy. Vitamin B3 is necessary for normal neurological and psychological functions and supports DNA repair and skin health.
Nicotinamide is a precursor in the production of coenzymes Nicotinamide adenine dinucleotide (NAD) and Nicotinamide adenine dinucleotide phosphate (NADP). These coenzymes play a crucial role in mitochondria production of ATP cellular energy.
Supplementation with vitamin B3 may also support the biosynthesis of monoamine neurotransmitters, such as serotonin. A deficiency in vitamin B3 can result in the body using tryptophan stores to synthesize its vitamin B3. This inefficient process can lead to a depletion of tryptophan, limiting the amount available for the synthesis of the feel-good neurotransmitter serotonin.
Vitamin B5 also known as pantothenic acid, is required by the body to synthesize coenzyme-A (CoA). CoA is essential to many life-sustaining biochemical processes, including the production of ATP cellular energy. CoA is necessary for the synthesis of fatty acids, cholesterol, and stress hormones. CoA is also required to convert choline into neurotransmitter acetylcholine, associated with learning, memory, and focus.
Active Form Vitamin B6 (Pyridoxal 5’-phosphate)
Brain Energy contains the bio-activated form of vitamin B6 known as Pyridoxal 5’-phosphate (P5P), allowing for immediate utilization in the body. P5P drives more than 150 vital enzyme activities and is predominantly involved in amino acid metabolism.
P5P helps synthesize neurotransmitters such as serotonin and GABA. It is also required in myelin sheath formation, the insulating layer that forms around nerve cells and supports efficient electrical impulses.
Vitamin B6 helps to regulate homocysteine levels via the transsulfuration pathway, where homocysteine is converted into cysteine and then ultimately into the master antioxidant, glutathione.
Vitamin B6 supports the normal functioning of the nervous and immune systems and contributes to healthy psychological function, hemoglobin production, and regulation of hormonal activity.
Active Form Vitamin B12 (Methylcobalamin)
Brain Energy contains the bio-activated form of vitamin B12 known as methylcobalamin, allowing for immediate utilization in the body. This form bypasses any potential absorption impact from a genetic polymorphism such as the MTHFR genetic defect.
Vitamin B12 deficiency is a recognized factor in cognitive decline with low blood serum levels associated with a higher risk of certain neurodegenerative and mental disorders.
Vitamin B12 plays a vital role in red blood cell formation and the remethylation of homocysteine. It supports the neurological structure and its healthy function.
Also referred to as vitamin B7, biotin contributes to macronutrient metabolism and ATP cellular energy production. It is a cofactor in several key enzymes, required in the metabolism of carbohydrates, fats, and proteins.
The high dose of biotin in Brain Energy supports the health of hair, skin, and nails. It also supports the nervous system and helps maintain normal psychological function.
Chromium supports the regulation of healthy blood sugar levels and contributes to the metabolism of glucose and fats. Research supports increased efficacy when combined with biotin, which may also assist with chromium absorption. Chromium is a required component of glucose tolerance factor (GTF), which helps maintain healthy blood sugar levels.